LIVER FIBROSIS, FIBROSIS-4 (FIB-4) INDEX PANEL

Test Code

LAB3968

Quest Code

30555

CPT Codes
84450, 84460, 85049

Includes

Aspartate Aminotransferase (AST)
Alanine Aminotransferase (ALT)
Platelet Count
FIB 4 Index

Preferred Specimen

1 mL serum collected in a serum separator tube (SST) and whole blood full EDTA (lavender-top) tube

Minimum Volume

0.5 mL serum • 0.5 mL microtainer-lavender or 1 mL EDTA whole blood

Other Acceptable Specimens

Whole blood from a full EDTA (tan-top) tube

Instructions

Note: If drawn with lead testing, EDTA (tan-top) is required

Transport Container

Serum separator tube (SST) and EDTA (lavender-top) tube

Transport Temperature

Serum: Refrigerated
Whole blood: Room temperature

Specimen Stability

Serum
Room temperature: 72 hours
Refrigerated: 5 days
Frozen: Unacceptable

Whole blood
Room temperature: 48 hours

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

See individual tests

Methodology
Spectrophotometry (SP) • Electronic Sizing and Counting/Cytometry/Microscopy

Reference Range

See Laboratory Report

Clinical Significance

The FIB-4 index is a simple non-invasive approach using selected laboratory measures (AST, ALT, platelet count) in combination with patient age to assess if an individual is at higher risk for advanced liver fibrosis (F3-F4).

Performing Laboratory

Quest Diagnostics-Lenexa

10101 Renner Blvd

Lenexa, KS 66219-9752

Last Updated: December 22, 2021

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.