COMPLEMENT C3/C4 PANEL

Test Code
LAB2050


Quest Code
5704


CPT Codes
86160 (x2)

Preferred Specimen
1 mL serum


Minimum Volume
0.5 mL


Transport Container
Transport tube


Transport Temperature

Refrigerated (cold packs)



Specimen Stability
Room temperature: Unacceptable
Refrigerated: 8 days
Frozen: 8 days


Methodology
Immunoturbidimetric

Reference Range
See individual tests


Clinical Significance
Decreased concentrations of both C3 and C4 suggest activation of the classical pathway, whereas decreased concentration of just C3 suggests activation of the alternative pathway. Both complement factors may be used to monitor activity of patients with systemic lupus erythematosus (SLE) and immune complex-induced vasculitis.



Last Updated: August 13, 2021


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.