HEXOSAMINIDASE

Test Code

LAB2061

Quest Code

34841

CPT Codes
83080 (x2)

Preferred Specimen

1 mL serum

Minimum Volume

0.5 mL

Instructions

If females wish screening for carrier status of Hexosaminidase A Deficiency, they must be tested prior to pregnancy. If the female is pregnant, we strongly suggest that her mate be tested for carrier status. Positive (or ambiguous) findings in the mate indicate a second order test on the female with leukocyte preparations.
Refer to 16330 (Mayo code NAGR) Hexosaminidase A and Total, Leukocytes/Molecular Reflex or 34842 (Mayo code NAGW) Hexosaminidase A and Total Hexosaminidase, Leukocytes for carrier detection and diagnosis of Tay-Sachs disease.

Note: Serum assay results are often ambiguous on pregnant females and will not be run.

New York state clients: Informed consent is required. Please document on the request form or electronic order that a copy is on file.

Transport Container

Transport tube

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Grossly icteric

Methodology
Heat Inactivation • Fluorometric • Automated

Setup Schedule

Varies

Report Available

8-15 days

Reference Range

Hexosaminidase Total
≤15 years	≥20 nmol/min/mL
≥16 years	10.4-23.8 nmol/min/mL
Hexosaminidase Percent A
≤15 years	20-90%
≥16 years	56-80%

Performing Laboratory

Mayo Clinical Laboratories

200 1st Street SW

Rochester, MN 55905-0001

Last Updated: August 13, 2021

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.