PARIETAL CELL ANTIBODY

Test Code
LAB1489


Quest Code
15114


CPT Codes
83516

Preferred Specimen
1 mL serum


Minimum Volume
0.3 mL


Transport Container
Transport tube


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Room temperature: 8 hours
Refrigerated: 14 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Lipemia • Received room temperature


Methodology
Immunoassay  (IA)

Setup Schedule
a.m. Tues, Thurs, Sat


Report Available
3-6 days


Reference Range
≤20.0 U Negative
20.1-24.9 U    Equivocal
≥25.0 U Positive


Clinical Significance

Gastric Parietal Cell Antibodies are found in 90% of patients with pernicious anemia. They are also found in autoimmune chronic atrophic gastritis preceding pernicious anemia. The antigenic target is the H+/K+ ATPase gastric proton pump responsible for parietal cell acid generation in the stomach.



Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042



Last Updated: August 13, 2021


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.