HPV GENOTYPES 16, 18/45, POST-HYST

Test Code

LAB4206

Quest Code

93102

CPT Codes
87625

Preferred Specimen

Vaginal specimen collected in 3 mL PreservCyt® transport medium (Thin Prep®) vial

Minimum Volume

1.5 mL

Instructions

Transfer 1 mL aliquot into an Aptima® transfer tube (containing 3 mL STM) within 30 days of collection.
Labs performing cytology: Aliquot PerservCyt® solution before or after performance of liquid based cytology testing.

Transport Container

PerservCyt® transport medium (Thin Prep®) vial

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 30 days
Refrigerated: 30 days
Frozen: Not established

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Swabs in Digene HC Cervical Sampler • Digene vials • Swab in SurePath™ vials • Received frozen

Methodology
Transcription-Mediated Amplification (TMA)

Setup Schedule

Tues, Thurs, Sat

Reference Range

HPV 16 RNA, Vaginal	Not detected
HPV 18/45 RNA, Vaginal	Not detected

Clinical Significance

Assay is used in combination with cytology to assess the presence or absence of high-risk HPV genotypes 16, 18, and/or 45 in post-hysterectomy patients. This information, together with physician's assessment of cytology history, other risk factors, and professional guidelines, may be used to guide patient management.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

Last Updated: January 21, 2026

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.