Vitamin E (Tocopherol) : 931

Test Code
VITEQ or 931

Alias/See Also
Alpha Tocopherol; Beta Tocopherol; Gamma Tocopherol

CPT Codes
84446

Instructions
Overnight fasting is preferred.

Serum separator tube or plain red tube.

Transport Container
Centrifuge serum separator or plain red tube and transfer 2 mL (Min: 0.7 mL) serum into an amber standard transport tube (preferred). If amber tube is not available, wrap tube in aluminum foil or place in an amber bag to protect from light.

Transport Temperature
Refrigerated.

Specimen Stability
Ambient: 24 hours; Refrigerated: 7 days; Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature; Not protected from light;  Plasma; Contaminated, grossly-hemolyzed or heavily-lipemic sera

Methodology
High Performance Liquid Chromatography (HPLC)

Setup Schedule
Monday - Saturday

Report Available
2-3 days (From receipt at performing laboratory)

Reference Range
Alpha-Tocopherol
Adult 5.7-19.9 mg/L
Pediatric
Term Infants (Cord Blood) 1.8-5.8 mg/L
4 Months-1 Year ≤9.1 mg/L
1-2 Years 2.9-16.6 mg/L
3-5 Years 5.5-11.8 mg/L
6-8 Years 4.6-14.8 mg/L
9-11 Years 6.2-14.3 mg/L
12-17 Years 3.7-12.4 mg/L

Levels of alpha-tocopherol less than 5 mg/L are consistent with Vitamin E deficiency in adults

Beta-Gamma-Tocopherol
Adult less than or equal to 4.3 mg/L
Pediatric 3-17 Years 0.5-3.8 mg/L


Clinical Significance
Deficiency of vitamin E may cause extensive neuropathy in young children and, in addition, is suspect as a possible cause of motor and sensory neuropathy in older children and in adults. One likely cause of vitamin E deficiency is intestinal malabsorption, resulting from bowel disease, pancreatic disease, or chronic cholestasis. Other causes of malabsorption of vitamin E include celiac disease, cystic fibrosis, and intestinal lymphangiectasia.

Performing Laboratory
Quest Diagnostics



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.