17-Hydroxypregnenolone : 1015296

Test Code
17OHPQ or 1015296

CPT Codes
84143

Instructions
Plain red.

Transport Container
Centrifuge plain red and aliquot 2 mL (Min: 0.4 mL) serum into a standard transport tube.

Transport Temperature
Refrigerated.

Specimen Stability
Ambient: 7 days; Refrigerated: 14 days; Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis, grossly lipemic, grossly icteric, serum separator tube.

Methodology
Chromatography/Mass Spectrometry

Setup Schedule
Sunday - Friday

Report Available
2-5 days (From receipt at performing laboratory)

Limitations
Infants with 21-hydroxylase deficiency may present with non-elevated results.

Reference Range
Effective 12/10/2018
Adult    
Male:   < or = 700 ng/dL
Female, Pre-Menopausal Mid Follicular :  38-378 ng/dL
Female, Pre-Menopausal Surge :  33-583 ng/dL
Female, Pre-Menopausal Mid Luteal :  70-470 ng/dL

Pediatric    see report

Clinical Significance
17-Hydroxypregnenolone is useful in the diagnosis of 3-Beta-Hydroxylase enzyme deficiency, a rare cause of congenital adrenal hyperplasia, and 17-Hydroxylase (P450c17) enzyme deficiency.

Performing Laboratory
Quest Diagnostics



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.