Adenosine Deaminase, RBC

Test Code
ADD (39148)

Quest Code

CPT Codes
84311<br /> **This test is not available for New York patient testing**

Preferred Specimen
1 mL whole blood collected in an EDTA (lavender-top or pink-top), or sodium or lithium heparin (green-top) tube

Minimum Volume
1 mL

Transport Temperature
Room temperature

Specimen Stability
Room temperature: 15 days
Refrigerated: 15 days
Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolyzed specimens

Kinetic Spectrophotometry

FDA Status
This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Setup Schedule
Sun, Tue, Thu

Report Available
3 to 6 Day(s)

Reference Range
400-900 mU/g Hb

Clinical Significance
Adenosine Deaminase (ADA) deficiency is an autosomal recessive disorder of purine metabolism primarily affecting lymphocyte development, viability, and function. Affected individuals have less than 1 percent of normal ADA catalytic activity in red cell hemolysates. ADA deficiency is the cause of 20-30 percent of SCID cases. If the patient has been recently transfused, ADA deficiency may be masked; interpret results with caution. Heterozygotes cannot be identified by this test.

Performing Laboratory
ARUP Laboratories
500 Chipeta Way
Salt Lake City, UT 84108

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.