Corticosterone

Test Code
CORTICOSTERONE (6547)

Quest Code
6547

CPT Codes
82528

Preferred Specimen
1 mL serum collected in a red-top tube (no gel)

Patient Preparation
An early morning specimen is preferred.

Minimum Volume
0.25 mL

Other Acceptable Specimens
Plasma collected in an: EDTA (lavender-top) tube or EDTA (royal blue-top) tube or sodium or lithium heparin (green-top) tube

Instructions
Separate serum after clotting.

Transport Temperature
Room temperature

Specimen Stability
Room temperature: 28 days
Refrigerated: 28 days
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tube (SST) • Do not submit glass tubes

Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Tue

Report Available
2 to 10 Day(s)

Reference Range
See Laboratory Report

Clinical Significance
Measurement of corticosterone may help confirm the diagnosis of the very rare aldosterone deficiency disorder, corticosterone methyl oxidase (18-hydroxylase) enzyme deficiency where the ratio of corticosterone to 18-hydroxycosticosterone may be increased.

Performing Laboratory
Quest Diagnostics Nichols Institute San Juan Capistrano
33608 Ortega Hwy
San Juan Capistrano, CA 92675-2042



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.