Chlamydiae Species, Culture


Test Code

Quest Code

CPT Codes
87110, 87140

Preferred Specimen
Endocervical, endourethral, or rectal mucosa (without feces) swab collected in a VCM or equivalent

Minimum Volume
1 swab

Other Acceptable Specimens
Vaginal swab on children <13 years old

Place swab into VCM (equal volumes of fluid and VCM) or equivalent and transport the specimen to the laboratory as soon as possible. Best recovery is obtained when the specimens are refrigerated at 2-8°C prior to shipment. Specimens in VCM or equivalent should be frozen at -70°C or colder and transported on dry ice. Storage or transport at -20 °C is not acceptable.

Note: Due to potential propagation of SARS-CoV-2 virus in Chlamydia culture cells, respiratory and eye specimens are no longer accepted. The recommended alternative for respiratory and eye specimens is 4966-Chlamydia trachomatis Antigen, DFA.

Transport Temperature
Frozen -70° C (dry ice)

Specimen Stability
Room temperature: Unacceptable
Refrigerated: 48 hours
Frozen -20° C: Unacceptable
Frozen -70° C: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Specimens submitted in viral transport media that do not support Chlamydia • Wooden shaft and calcium alginate swabs • Bacterial transport systems • Molecular transport systems • Respiratory specimens • Eye (conjunctival) specimens

Centrifugation-Enhanced Culture with Monoclonal Antibody Detection

Setup Schedule

Report Available
3 to 4 Day(s)

Reference Range
See Laboratory Report

Clinical Significance
C. trachomatis is associated with infections of the mucous membranes of the urogenital system, the upper respiratory tract and the eye. It may be sexually transmitted; resulting diseases include urethritis, cervicitis, salpingitis, epididymitis, proctitis and lymphogranuloma venereum. C. pneumoniae is associated with both upper and lower respiratory infections. Infections of the upper respiratory tract and eye usually occur in newborns exposed at parturition. In adults, eye infection may be transmitted by hand after contact with secretions. Isolation by tissue culture is recommended when testing individuals for legal purposes.

Performing Laboratory
Quest Diagnostics Infectious Disease, Inc.
33608 Ortega Highway, Bldg B-West Wing
San Juan Capistrano, 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.