Coxsackie A Antibodies, Serum

Test Code
COXA AB PROF(37477)

Quest Code
37477

CPT Codes
86658 (x6)

Includes
Coxsackie Antibodies A2, A4, A7, A9, A10, A16

Preferred Specimen
2 mL serum

Minimum Volume
1 mL

Transport Container
Transport tube

Transport Temperature
Room temperature

Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Methodology
Complement Fixation (CF)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Tue-Sat

Report Available
2 to 5 Day(s)

Limitations
Culture does not usually support growth of coxsackie A viruses.

Reference Range
Coxsackie A2 Ab <1:8
Coxsackie A4 Ab <1:8
Coxsackie A7 Ab <1:8
Coxsackie A9 Ab <1:8
Coxsackie A10 Ab <1:8
Coxsackie A16 Ab <1:8


Clinical Significance
Panel currently includes testing against A-2, 4, 7, 9, 10, and 16 antigens. Although there is cross-reactivity among the enteroviruses by CF, most healthy people do not have titers >1:8. Therefore, detectable titers, especially those >1:32, should be considered diagnostic. Confirmed serodiagnosis is made by demonstration of a four-fold change in titers between acute and convalescent sera.

Performing Laboratory
Quest Diagnostics Infectious Disease, Inc.
33608 Ortega Highway, Bldg B-West Wing
San Juan Capistrano, 92675-2042



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.