Acetone

Message
NOTE TUBE TYPE CHANGE 2/25/2019
GRAY TOP REQUIRED
 

Test Code
ACE(205)

Quest Code
205

CPT Codes
82010

Preferred Specimen
1 mL whole blood collected in a fluoride oxalate (gray-top) tube

Patient Preparation
Do not use alcohol solutions as skin preparation for drawing specimens. Use non-alcohol solutions such as Betadine® or Zephiran®. Keep transport container tightly sealed.

Minimum Volume
0.5 mL

Other Acceptable Specimens
Plasma collected in an: EDTA (lavender-top) tube • Serum collected in a red-top tube (no gel) • Whole blood collected in a potassium oxalate (gray-top) tube

Instructions
Do not open. Keep specimen tightly capped. Prevent exposure to atmosphere.

Transport Temperature
Room temperature

Specimen Stability
Room temperature: 14 days
Refrigerated: 14 days

Methodology
Chromatography

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Sun-Sat

Report Available
3 to 4 Day(s)

Limitations
Patients with diabetes who may also have lactic acidosis may have false negatives or falsely weak reactions. With these patients a beta-hydroxybutyrate measurement may be preferred. High concentrations of levodopa may produce false positives. Ketogenic or low/no-carb diets, often instituted for pediatric epilepsy, may also produce false positive results.

Reference Range
None detected

Clinical Significance
Excessive formation of ketone bodies (acetone) results in increased blood levels (ketonemia) and increased excretion in the urine (ketonuria). This condition is associated with a decreased availability of carbohydrates, such as dieting or decreased use of carbohydrates. Diabetes and alcohol consumption are common causes of ketoacidosis. Acetone is one ketone body formed from acetoacetate. Ingestion of isopropyl alcohol also leads to the formation of acetone.

Performing Laboratory
Quest Diagnostics Nichols Institute Chantilly
14225 Newbrook Dr
Chantilly, VA 20153



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.