Cortisol, Free, LC/MS, Serum

Test Code
CORTFR(36423)

Quest Code
36423

CPT Codes
82530

Preferred Specimen
2 mL serum collected in a red-top tube (no gel)

Minimum Volume
0.7 mL

Other Acceptable Specimens
Plasma collected in an: EDTA (lavender-top) tube or PPT Potassium EDTA (white-top) tube

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Room temperature: 4 hours
Refrigerated: 7 days
Frozen: 2 years

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Received room temperature • Serum separator tube (SST)

Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Sun-Thu

Report Available
3 to 7 Day(s)

Reference Range
Adult    
8:00 A.M.-10:00 A.M. 0.07-0.93 µg/dL
4:00 P.M.-6:00 P.M. 0.04-0.45 µg/dL
10:00 P.M.-11:00 P.M. 0.04-0.35 µg/dL


Clinical Significance
Free cortisol is useful in the detection of patients with Cushing's syndrome for whom free cortisol concentrations are elevated.

Performing Laboratory
Quest Diagnostics Nichols Institute San Juan Capistrano
33608 Ortega Hwy
San Juan Capistrano, CA 92675-2042



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.