Copper, 24-Hour Urine

Test Code
COPU (365)

Quest Code

CPT Codes

CPT code 81050 may be added at an additional charge for volume measurement

Preferred Specimen
7 mL aliquot of a well mixed 24 hour urine collected in acid washed or metal free container

Minimum Volume
3 mL

Collect without preservative and transport in a plastic, acid washed, metal free container. Record total volume on specimen container and on test requisition. Random urine is not acceptable. To avoid contamination, do not measure 24-hour volume.

Transport Temperature
Room temperature

Specimen Stability
Room temperature: 5 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Fecal contamination

Inductively Coupled Plasma/Mass Spectrometry (ICP/MS)

Setup Schedule
Sun, Wed, Fri

Report Available
1 to 4 Day(s)

Reference Range
15-60 mcg/24 h

Clinical Significance
Copper is an essential element that is a cofactor of many enzymes. Copper metabolism is disturbed in Wilson's disease, Menkes disease, primary biliary cirrhosis, and Indian childhood cirrhosis. Urinary copper concentrations are also useful to monitor patients on chealation therapy.

Performing Laboratory
Quest Diagnostics Nichols Institute
27027 Tourney Road
Valencia, CA 91355-5386

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.