Vitamin K

Test Code
VITK (36585)

Quest Code

CPT Codes

Preferred Specimen
3 mL plasma collected in an EDTA (lavender-top) tube - protect from light

Patient Preparation
Fasting for a minimum of 8 hours.
Patient should refrain from eating liver and taking multivitamins or vitamin K at least 24 hours before sample collection.

Minimum Volume
1.5 mL

Other Acceptable Specimens
Plasma collected in a sodium or lithium heparin (green-top) tube

Centrifuge within 1 hour of collection. Immediately separate plasma from the cells into a clean, plastic transport tube. Freeze. Protect from light.
If unable to centrifuge immediately, sample should be covered with aluminum foil immediately and placed on ice until plasma can be separated from cells. Transport to the laboratory frozen.

Transport Container
Plastic screw-cap vial- protect from light

Transport Temperature

Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 90 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Serum


FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Report Available
4 to 5 Day(s)

Reference Range
80-1160 pg/mL

Clinical Significance
Vitamin K is a required co-factor for the synthesis of factors 2, 7, 9, and 10 and proteins C and S. Deficiencies of vitamin K lead to bleeding. Coumadin® (warfarin) acts as an anticoagulant because it is a vitamin K antagonist.

Performing Laboratory
Quest Diagnostics Nichols Institute
27027 Tourney Road
Valencia, CA 91355-5386

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.