CALPROTECTIN, STOOL

Test Code
CALPR (16796)

Quest Code
16796

CPT Codes
83993

Preferred Specimen
3 grams solid stool collected in a clean leak-proof, plastic screw-cap container without preservative

Minimum Volume
0.3 g

Other Acceptable Specimens
Liquid or semi-liquid stool

Instructions
Collect stool specimen in a clean leak-proof plastic screw-cap container without preservative.

Quest standard container stock clerk # 205299 is available through Client Supply.

Room temperature stability: Stable for 6 days. However due to the sample type, it is not recommended to keep stool sample at Room Temperature.

Transport Temperature
Frozen

Specimen Stability
Room temperature: See instructions
Refrigerated: 7 days
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Stool specimen collected in a container with fixative or preservative

Methodology
Chemiluminescence (CL)

Setup Schedule
Sun-Thu

Report Available
3 to 6 Day(s)

Limitations
NSAIDs may cause elevated results.

Reference Range
<50 mcg/g Normal
50-120 mcg/g Borderline
>120 mcg/g Elevated


Clinical Significance
Calprotectin is a non-specific marker of bowel inflammation. Subsequent to white blood cell migration into the intestine, this neutrophil protein may be detected in the stool. Thus, fecal calprotectin levels may assist in diagnosis of inflammatory bowel disease; Crohn's disease and ulcerative colitis and other disorders characterized by bowel inflammation. It can also be used as an aid in the differentiation of IBD from irritable bowel syndrome.

Performing Laboratory
Quest Diagnostics Nichols Institute San Juan Capistrano
33608 Ortega Hwy
San Juan Capistrano, CA 92675-2042



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.