VMA (Vanillylmandelic Acid), Random Urine

Test Code
VMAR (Vanillylmandelic Acid), Random Urine (1710)

Quest Code

CPT Codes
84585, 82570


Preferred Specimen
10 mL urine with 6N HCl collected in a plastic screw-cap container

Patient Preparation
It is preferable for the patient to be off medications for three days prior to collection. However, common antihypertensives (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blockers) cause minimal or no interference. Patient should avoid alcohol, coffee, tea, tobacco (including use of nicotine patch), bananas, citrus fruits and strenuous exercise prior to collection.

Minimum Volume
5 mL

Other Acceptable Specimens
Unpreserved urine

10 mL urine: pH adjusted to <3.0 using 6N HCl Urine without preservative is acceptable if pH is below 6 and the sample is shipped frozen.

Transport Temperature
Preserved urine: Room temperature
Unpreserved urine: Fozen

Specimen Stability
Room temperature: 10 days
Refrigerated: 14 days
Frozen: 1 year

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
pH >3.0 • Received unfrozen

High Performance Liquid Chromatography (HPLC)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Report Available
3 to 6 Day(s)

Reference Range
See Laboratory Report

Clinical Significance
Vanillylmandelic acid (VMA) is the major urinary product resulting from the metabolic degradation of catecholamine, norepinephrine and epinephrine. Elevated concentrations of VMA are commonly found in cases of catecholamine secreting tumors such as pheochromocytoma, neuroblastoma, and ganglioneuroma.

Performing Laboratory
Quest Diagnostics Nichols Institute San Juan Capistrano
33608 Ortega Hwy
San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.