CATECHOLAMINES, FRACTIONATED, 24-HOUR URINE

Test Code
CATFU 24HR Urine (39627)

Quest Code
39627

CPT Codes
82384 82570

Includes
Creatinine, Norepinephrine, Epinephrine, Dopamine, and Total Catecholamines (calculated)

CPT code 81050 may be added at an additional charge for volume measurement

Preferred Specimen
Urine with HCL 24 hour 10 mL

INSTRUCTIONS:
Collect 24-hour urine with 25 mL of 6N HCL to maintain a
pH below 3. Urine without preservative is acceptable if pH
is below 6 and the sample is shipped frozen. Record
24-hour urine volume on test request form and urine vial.
It is preferable for the patient to be off medications for
three days prior to collection. However, common
antihypertensives (diuretics, ACE inhibitors, calcium
channel blockers, alpha and beta blockers) cause minimal
or no interference.

NOTE:
Transport Temperature: Room temperature

Methodology: Ultra Performance Liquid Chromatography
(UPLC), Electrochemical Detection, Kinetic Alkaline Picrate

Minimum Volume
5 mL Urine with HCL 24 hour

Transport Container
Sterile

Specimen Stability
Frozen - 49 Day(s)
Refrigerated - 30 Day(s)
Room Temperature - 7 Day(s)

Methodology
High Performance Liquid Chromatography (HPLC)

Setup Schedule
Mon-Fri

Report Available
3 to 5 Day(s)

Limitations
Recent surgery, traumatic injury, upright posture, cold, anxiety, pain, clonidine withdrawal, and concurrent acute or chronic illness may produce elevated results..

Reference Range
See Laboratory Report

Clinical Significance
The three catecholamines (norepinephrine, epinephrine, and
dopamine) are the principal secretory products of neural
tissue. Clinically, the measurement of circulating
catecholamines is valuable in the diagnosis of
catecholamine secreting tumors associated chiefly with
hypertension (pheochromocytomas, neuroblastomas, and
gangliomas) and with the evaluation of orthostatic
hypotension.

Performing Laboratory
QUEST DIAGNOSTICS-NICHOLS INST 33608 ORTEGA HIGHWAY SAN JUAN CAPISTRANO, CA 92675



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.