Clozapine

Test Code
CLOZ (4964)

Quest Code
4964

CPT Codes
80159

Includes
Clozapine and Norclozapine

Preferred Specimen
2 mL serum collected in a red-top tube (no gel)

Minimum Volume
1 mL

Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top) tube, sodium heparin (green-top) tube or lithium heparin (green-top) tube

Instructions
Do not use gel barrier/ Serum Separator tubes (SST®)

Specimen Stability
Room temperature: 24 hours
Refrigerated: 5 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Gel barrier/Serum Separator Tube (SST®)

Methodology
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Setup Schedule
Set up: Tues-Sat; Report available: 1-3 days

Reference Range
Norclozapine 25-400 mcg/L
Clozapine See Laboratory Report


Clinical Significance
Clozapine is an atypical antipsychotic agent. Norclozapine has minimal therapeutic activity.

Performing Laboratory
Quest Diagnostics Nichols Institute
27027 Tourney Road
Valencia, CA 91355-5386



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.