Chlordiazepoxide and Metabolites

Test Code

Quest Code

CPT Codes

Chlordiazepoxide, Norchlordiazepoxide, Nordiazepam

Preferred Specimen
2 mL serum collected in a red top tube (no gel)

Patient Preparation
Collect at trough concentration, i.e., just before the administration of the next dose.

Minimum Volume
1 mL

Serum separator tubes are not acceptable; use polypropylene tubes and ship on cold pack by overnight courier

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Refrigerated: 5 days
Frozen: 14 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature • Serum Separator Tube (SST®

Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Report Available
1 to 6 Day(s)

Reference Range
Chlordiazepoxide 100-3000 ng/mL
Norchlordiazepoxide 100-3000 ng/mL
Nordiazepam 100-1500 ng/mL

Clinical Significance
For therapeutic drug monitoring of anxiolytic drug. Peak concentrations are reached serveral hours after oral administration. Elimination half-life is 24-48 hours.

Performing Laboratory

Quest Diagnostics Nichols Institute
27027 Tourney Road
Valencia, CA 91355-5386

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.