Carboxyhemoglobin, Blood

Test Code

Quest Code

CPT Codes

Preferred Specimen
One full EDTA (lavender-top) tube of whole blood

Minimum Volume
0.5 mL

Other Acceptable Specimens

Sodium heparin (green-top) tube

Keep tube closed

Transport Temperature
Room temperature

Specimen Stability
Room temperature: 5 days
Refrigerated: 10 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Fluoride oxalate (gray-top) tube • Grossly clotted

Spectrophotometry (SP)

Setup Schedule

Report Available
1 to 2 Day(s)

Reference Range
Non-Smoker <2 % of total Hgb
Average Smoker  4-5 % of total Hgb
Heavy Smoker 8-12 % of total Hgb
Potentially Toxic >15 % of total Hgb

Clinical Significance
Carbon monoxide is the most common of the gaseous poisons. Malfunctioning or poorly ventilated heating appliances and internal combustion engines are frequent causes of carbon monoxide poisoning. Carbon monoxide combines reversibly with hemoglobin in a manner almost identical to oxygen resulting in a decrease in the amount of oxygen carried by hemoglobin. Accidental poisoning can occur even at low levels (greater than 0.01%) of CO in the atmosphere with prolonged exposure.

Performing Laboratory
Quest Diagnostics Chantilly
14225 Newbrook Dr.
Chantilly, VA 20153-0841

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.