Test Code
CMV DNA PCR (10601)

Quest Code

Alias/See Also

CPT Codes

Preferred Specimen
1 mL whole blood collected in an EDTA (lavender-top), or ACD (yellow-top) tube
1 mL plasma collected in an EDTA (lavender-top), ACD (yellow-top), or EDTA PPT (white-top) tube
Serum, CSF, amniotic fluid, random urine, amniotic fluid supernatant, bronchoalveolar lavage, or eye fluids submitted in a sterile, leak-proof container

Minimum Volume
0.5 mL

Other Acceptable Specimens
3 mm frozen fresh tissue

Blood collected in tubes with heparin anticoagulant are not accepted for this test.

Plasma: Collect blood in sterile tubes containing EDTA or ACD as anticoagulant or in Plasma Preparation Tubes (PPTs). Store collected whole blood at room temperature and separate plasma from cells within 2 hours of collection. Transfer plasma to sterile, plastic, screw-capped tubes and store refrigerated or frozen. If blood is collected in a PPT tube, centrifuge within 2 hours of collection and store refrigerated or frozen. It is not necessary to transfer the plasma from a PPT tube to aliquot tubes.
Whole blood: Collect whole blood in sterile tubes containing EDTA or ACD as anticoagulant. Store refrigerated. Do not freeze whole blood.
CSF, amniotic fluid, urine and tissue: Collect in a sterile container and store refrigerated or frozen.

Transport Temperature
Refrigerated (cold packs): Whole blood, plasma, amniotic fluid, CSF, serum, and random urine
Frozen: Tissue

Specimen Stability
Whole blood
Room temperature: 48 hours
Refrigerated: 8 days
Frozen: Unacceptable
Other sample types
Room temperature: 48 hours
Refrigerated: 8 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Heparinized specimens • Unspun PPT tube

Real-Time Polymerase Chain Reaction

Setup Schedule

Reference Range
Not detected

Clinical Significance
In patients who are immunocompromised, CMV may cause disseminated, severe disease. CMV is also the most common cause of congenital viral infection in humans. Quantitative PCR methods may be useful in monitoring CMV replication in immunosuppressed patients or in determining the viral load of CMV in amniotic fluid.

Performing Laboratory
Quest Diagnostics Infectious Disease, Inc.
33608 Ortega Highway, Bldg B-West Wing
San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.