Chymotrypsin, Stool [11235X]

Test Code

Quest Code

CPT Codes

Preferred Specimen
1 gram stool collected in a sterile leak-proof feces container

Patient Preparation
Patients receiving pancreatic enzymes should discontinue taking the enzymes at least 5 days before collection.

Minimum Volume
0.5 mL

Specimen Stability
Refrigerated: 14 days
Frozen: 30 days


Setup Schedule

Report Available
2 to 2 days

Reference Range
Chymotrypsin Stool: 2.3 - 51.4 U/g

Clinical Significance
The diagnosis of chronic pancreatitis depends upon the demonstration of functional impairment of the pancreas. Impairment is determined by several means, two of which are: 1. Direct measurement of exocrine secretion into the duodenum after stimulation by a standard meal or after stimulation by intravenous secretin/pancreozymin; 2. The direct measurement of the activities of certain enzymes in feces. Chymotrypsin activity in stool, for example, has been shown to be lower than normal in patients with pancreatic exocrine insufficiency.

Performing Laboratory
Quest Diagnostics Nichols Institute San Juan Capistrano
33608 Ortega Highway
San Juan Capistrano, CA 92675

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.