ColoVantage® (Methylated Septin 9)

Test Code
SEPTIN 9 (16983)

Quest Code
16983

CPT Codes
81327<br /> ** This test code is for non-New York patient testing. For New York patient testing, use test code 16984. **

Preferred Specimen
10 mL frozen plasma collected in an EDTA (lavender-top) tube

Minimum Volume
5 mL

Instructions
This test requires 10 mL of plasma (minimum volume 5 mL). Specimens with less than 5 mL of plasma will be rejected. To obtain this volume of plasma, collect blood in two (2) 10 mL EDTA (lavender-top) tubes or five (5) standard EDTA (lavender-top) tubes. Centrifuge the blood samples, separate plasma and combine them. Send plasma in a single 10 mL pour-off tube. If a 10 mL pour-off tube is not available, two (2) 5 mL pour-off tubes can be used.

Transport Temperature
Frozen

Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 28 days

Methodology
Real-Time Polymerase Chain Reaction

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Daily; Report available: 4 days

Reference Range

Not detected



Clinical Significance
Methylated Septin 9 is a DNA marker associated with colorectal cancer.

Performing Laboratory
Quest Diagnostics Chantilly
14225 Newbrook Dr.
Chantilly, VA 20153-0841



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.