Coenzyme Q10

Test Code
CO Q10 (19826)

Quest Code
19826

CPT Codes
82542

Preferred Specimen
1 mL frozen serum in an amber vial

Patient Preparation
Patient should fast 8-12 hours prior to collection. Patient may have water. It is not necessary to discontinue nutritional supplements prior to this test.

Minimum Volume
0.5 mL

Instructions
Send serum in an amber vial or wrap a clear, plastic screw-cap vial in foil. Protect from light. Freeze and ship frozen.

Transport Temperature
Frozen

Specimen Stability
Frozen: 7 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Samples not protected from light

Methodology
High Performance Liquid Chromatography (HPLC)

Setup Schedule
Tue, Thu, Sat

Report Available
2 to 5 Day(s)

Reference Range

0.44-1.64 mg/L



Clinical Significance
Coenzyme Q10 (CoQ10) is a fat soluble cofacter that is essential for energy producing metabolic pathways and for the proper functioning of the mitochondrial oxidative system. With insufficient CoQ10, the electron transfer activity of the mitochondria decreases, resulting in a net failure to produce the energy necessary to run the cell. Tissues with high energy demand have even greater demands for CoQ10. For example, heart muscle, which continually exerts a pumping action for an entire lifetime, has an immense need for the cofactor. Studies demonstrate the effectiveness of supplemental coenzyme Q10 in cardiomyopathy, myocardial dysfunction, and congestive heart failure. CoQ10 is also a powerful antioxidant like vitamins E and C, and thus serves the role of neutralizing excess free radicals. It is now well established that the control of excessive free radical activity is key in preventing/delaying the progression of degenerative diseases.

Performing Laboratory
Quest Diagnostics Nichols Institute
27027 Tourney Road
Valencia, CA 91355-5386




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.