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PANCREASTATIN
MessageQUEST WILDCODE NEEDED.
Call Carrie x4171 or Amber x4173
Patients must be fasting 10-12 hours prior to collection of specimen. Patient should not be on any medications that may influence Insulin levels, if possible, for at least 48 hours prior to collection.
Call Carrie x4171 or Amber x4173
Patients must be fasting 10-12 hours prior to collection of specimen. Patient should not be on any medications that may influence Insulin levels, if possible, for at least 48 hours prior to collection.
Test Code
LAB00268
Alias/See Also
LAB00268
CPT Codes
86316
Preferred Specimen
2 mL Serum - Plain Red
Allowed to clot for 2 hours at room temp or overnight at 4C before centrifugation for 15 minutes.
Freeze Serum Immediately after centrifugation.
Allowed to clot for 2 hours at room temp or overnight at 4C before centrifugation for 15 minutes.
Freeze Serum Immediately after centrifugation.
Patient Preparation
Patients must be fasting 10-12 hours prior to collection of specimen. Patient should not be on any medications that may influence Insulin levels, if possible, for at least 48 hours prior to collection.
Minimum Volume
1.0 mL Serum
Other Acceptable Specimens
Marble/Gold
Instructions
Transport Temperature
Frozen
Specimen Stability
Frozen: 6 months
Clinical Significance
Pancreastatin is a 49 amino acid peptide produced by degradation of Chromo-granin A. It inhibits Chromogranin A and Parathyroid Hormone release. Pancreastatin also inhibits release of Somatostatin upon glucose stimulation. It may also control carbohydrate metabolism and hyperglycemia. Although there are no compounds with significant structural homology with Pancreastatin, there are minor similarities to Gastrin and Anti-Diuretic Hormone. Pancreastatin reduces the the early phase of Glucose induced Insulin release. Suppression of Insulin release upon Glucose stimulation is a characteristic feature of Type II Diabetes. Pancreastatin could play an important therapeutic role in the treatment of diabetes. Pancreastatin also inhibits release of Somatostatin. It may also control carbohydrate metabolism and hyperglycemia.
Performing Laboratory
Send to Quest Diagnostics, they will send onto BioAgilytix Diagnostics