P50 ERYTHROCYTES, OXY DISSOCIATION

Test Code
P50 ERYTHRO

Alias/See Also
OXYGEN DISSOCIATION, P50, ERYTHROCYTES

Preferred Specimen
WHOLE BLOOD

Instructions
COLLECT A NA GREEN TUBE ON A CONTROL PATIENT TO SEND WITH TEST PATIENT TO MAYO CLINIC. PATIENTS AGE AND SEX IS REQUIRED

Transport Container
NA GREEN

Transport Temperature
REF-72 HRS

Setup Schedule
Set Up:
Report Available:

Reference Range
P50 ERYTHROCYTES


Clinical Significance
Abnormal oxygen affinity is demonstrated in the presence of some hemoglobin variants:

-High oxygen affinity causes erythrocytosis
-Low oxygen affinity causes cyanosis

Increased oxygen affinity of hemoglobin, reflected in a low p50, left-shifted oxygen dissociation curve, and loss of normal sigmoidal configuration, are characteristic of many hemoglobin variants that are responsible for polycythemia. Measurement of oxygen affinity is the most important method for diagnosis of these disorders.



Performing Laboratory
MAYO CLINIC



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.