Hepatitis C RNA Genotype, LiPA

Test Code

4227

Alias/See Also

Sunquest;HCVGL
Quest:37811

CPT Codes
87902

Preferred Specimen

2 mL plasma collected in a PPT potassium EDTA (white-top) tube or EDTA (lavender-top) tube

Minimum Volume

0.6 mL

Other Acceptable Specimens

Plasma collected in: ACD-B (yellow-top) tube
Serum

Instructions

Separate plasma( preferred) or serum (acceptable) from whole blood within 24 hours of collection by centrifugation at 800-1600 x g for 20 minutes are room temperature. Transfer the plasma to a properly identified, sterile, polypropylene screw-cap vial and ship refrigerated or frozen.

Transport Container

Plastic Scree-cap vial

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room Temperature: 72 Hours
Refrigerated: 14 days
Frozen: 42 Days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Unspun PPT tube

Methodology
Multi-Probe Reverse Hybridization

FDA Status
This test was developed and it analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administrations. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes

Setup Schedule

Daily

Report Available

Reports in 3 days at Focus

Clinical Significance

Hepatitis C genotype is a predictor of response to interferon alfa-2b (non-type 1 are better responders) and to combination therapy with interferon and ribavirin (all types respond but dosage and duration of treatment is dependent on genotype; type 1 requires extended treatement).

Performing Laboratory
*** Central Lab will send to Quest ***

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.