Herpes Simplex Virus Type 1 and Type 2, IgG

Message
Performing Lab: Methodist Hospital


Test Code
LABS20471


Alias/See Also
Sunquest;HSVGT
EPIC;LABS20471


CPT Codes
HSV1=86695 HSV2=86696

Preferred Specimen
Serum collected in Serum Spearator Tube or Plain Red Top


Transport Temperature
Refrigerated


Specimen Stability
Refrigerated: 7 days
Frozen: More than 7 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Specimens other than Serum. Specimens exhibiting gross (4+) hemolysis, icterus or lipemia.


Methodology
Semi Quantitative Chemiluminescent Immunoassay

Setup Schedule
Monday - Friday


Report Available
Monday - Friday


Reference Range
HSV-1 Type specific IgG
 
Index Results Interpretation
<0.9 Negative (No further testing) No detectable antibodies to HSV-1 were found. A negative result generally indicates that the patient has not been infected, but does not always rule out acute HSV infection. If clinical exposure to HSV is suspected despite a negative finding, a second sample should be collected and tested no less than 4-6 weeks later.
0.9-1.10 Equivocal If equivocal, a second sample should be collected no less than 4-6 weeks later.
Greater than or equal to 1.10 Positive (No further testing) Indicates the presence of detectable IgG antibody to HSV-1







HSV-2 Type Specific IgG
 
Index Results Interpretation
<0.9 Negative (No further testing) No detectable antibodies to HSV-2 were found. A negative result generally indicates that the patient has not been infected, but does not always rule out acute HSV infection. If clinical exposure to HSV is suspected despite a negative finding, a second sample should be collected and tested no less than 4-6 weeks later.
0.9-1.10 Equivocal If equivocal, a second sample should be collected no less than 4-6 weeks later.
Greater than or equal to 1.10 Positive (No further testing) Indicates the presence of detectable IgG antibody to HSV-2

Note: The magnitude of the reported Index is not indicative of the amount of antibody present in the patient sample.
Seroconversion from a negative sample to a positive sample is evidence of either a recent infection or an acute infection. A positive result generally indicates exposure to HSV

Additional Information:
1.   Serological cross-reactivity has been noted in specimens containing antibody to Treponema pallidum and Candida albicans.
2.   Assay results should be used in conjunction with other clinical and laboratory data to assist the clinician in making individual patient management decision.
3.   The performance of this assay has not been established for monitoring HSV-1 therapy.
4.   Grossly hemolyzed, icteric or lipemic samples, as well as samples containing particulate matter or exhibiting obvious bacterial contamination should not be tested.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.