Prolactin Serial Dilultion

Message

Performing Lab: Central Lab

Test Code

5158

Alias/See Also

Sunquest: PROLD; Macroadenoma Prolactin Dilution Study

CPT Codes
84146

Preferred Specimen

0.2 mL Lithium Heparin Plasma (light green-top) tube

Minimum Volume

0.1 mL

Other Acceptable Specimens

Serum separator (gold-top), Red, Red/Gray

Instructions

Ordering:
To be ordered by Endocrinology and Neurosurgery Physicians only. If questions, discuss with Dr. Doug Olson at 651-254-9618

Transport Temperature

Refrigerated

Specimen Stability

Refrigerated: 7 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Icteric samples

Methodology
Chemiluminescence

Setup Schedule

Monday-Friday

Report Available

Same Day

Clinical Significance

Prolactin is released from the anterior pituitary under the inhibitory control of dopamine, which is secreted from the hypothalamus. When isolated from pituitary tissue, blood or amniotic fluid, prolactin has been found to exist in a number of molecular weight forms and has some structural similarities with human growth hormone. Prolactin plays a major role in the initiation and maintenance of lactation, where there is a physiological elevation of circulating concentrations. Pathological hyperprolactinemia occurs in hypothyroidism and renal failure. Hyperprolactinemia is also known to impair gonadal function in both sexes. Women may present with amenorrhea while men may suffer from impotence.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.