Anti-SSA Antibody

Message

Performing Lab: Central Lab

Test Code

4766

Alias/See Also

Sunquest: ROSSA; Anti-Ro Antibody, Sjögren's Antibody

CPT Codes
86235

Preferred Specimen

0.5 mL Serum Separator (gold-top) tube

Minimum Volume

0.2 mL

Other Acceptable Specimens

Red, Red/Gray

Transport Temperature

Refrigerated

Specimen Stability

Refrigerated: 7 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Plasma is not an acceptable specimen type. Hemolyzed or grossly lipemic samples

Methodology
Fluoroenzymeimmunoassay

Setup Schedule

Monday, Wednesday, Friday

Report Available

Same Day

Reference Range

0 - 6 U/mL: Negative
7 - 10 U/mL: Equivocal
>=11 U/mL: Positive

Clinical Significance

Detection of SS-A/Ro antibodies is of interest and significance for the clinical diagnosis of SLE (prevalence 40-50 %) and Sjögren's syndrome (prevalence 60-75 % for primary Sjögren's syndrome). It is used in conjunction with other laboratory and clinical findings. SS-A antibodies have been reported to occur in tight association with certain disease subsets, such as subacute cutaneous LE, neonatal lupus erythematosus or vasculitis in Sjögren's syndrome.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.