IgG (Immunoglobulin G)

Message

Performing Lab: Central Lab

Test Code

0518

Alias/See Also

Sunquest: IGG

CPT Codes
82784

Preferred Specimen

40 uL Lithium Heparin Plasma (light green-top) tube

Minimum Volume

40 uL (does not include dead volume)

Other Acceptable Specimens

Serum separator (gold-top), Red, Red/Gray

Transport Temperature

Refrigerated

Specimen Stability

Room Temperature: < 4 months
Refrigerated: < 8 months
Frozen: < 8 months

Methodology
Immunoturbidimetric

Setup Schedule

Monday - Friday

Report Available

Same day

Reference Range

Age	Sex	Reference Range
0-32 Days	Female	391-1737
32 Days - 2 Years	Female	203-934
2 Years - 3 Years	Female	483-1226
Greater than 3 Years	Female	552-1631
0-32 Days	Male	397-1765
32 Days - 2 Years	Male	205-948
2 Years - 3 Years	Male	475-1210
Greater than 3 Years	Male	540-1822

Clinical Significance

IgG is present in all extracellular fluids and accounts for 70 to 75% of the plasma immunoglobulins in adults. IgG functions to protect tissue spaces by eliminating small soluble proteins such as bacterial toxins and enhancing their clearance through the reticuloendothelial system. IgG levels may be elevated in recurrent or chronic infection, autoimmune diseases, and malignancies. Increased levels may also be observed in systemic lupus erythematosus, rheumatoid arthritis, some parasitic diseases, and infections. The most common form of multiple myeloma is the IgG type. Deficiency of IgG may be genetic (e.g., Wiskott-Aldrich syndrome, severe combined immunodeficiency) or acquired (e.g., AIDS).

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.