LH (Luteinizing Hormone)

Message

Performing Lab: Central Lab

Test Code

0197

Alias/See Also

Sunquest: LH

CPT Codes
83002

Preferred Specimen

0.2 mL Serum (gold-top) tube

Minimum Volume

165 uL

Transport Temperature

Refrigerated

Specimen Stability

Room Temperature: 24 hours
Refrigerated: 7 days
Frozen: 7 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross Hemolysis

Methodology
Chemiluminescent Microparticle Immunoassay (CMIA)

Setup Schedule

Monday - Friday

Report Available

Same day.

Reference Range

Follicular: 2 - 12 mIU/mL
Midcycle: 8 - 89 mIU/mL
Luteal: 0 - 14 mIU/mL
Postmenopausal: 5- 62 mIU/mL
Males : 0 - 12 mIU/mL

Clinical Significance

LH is a dimeric glycoprotein hormone secreted by the anterior pituitary in response to hypothalamic gonadotrophin releasing hormone. The a-subunit is common to other glycoprotein hormones, while the ß-subunit, which confers biological activity, has some homology with that of human chorionic gonadotrophin. During the menstrual cycle, follicle stimulating hormone (FSH) stimulates growth of the ovarian follicle which, when mature, ovulates in response to a surge of LH and, to a lesser extent, of FSH. Ovarian steroids are the primary negative feedback control for LH secretion. At menopause, reduced ovarian negative feedback results in elevated LH concentrations. LH concentrations also tend to be elevated in women of pre-menopausal age who experience ovarian failure, or whose ovaries failed to mature during puberty.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.