Hepatitis B Core Antibody

Message
Performing Lab: Central Lab


Test Code
0185


Alias/See Also
Sunquest: HBC; Anti-HBc; HBcAb


CPT Codes
86704

Preferred Specimen
0.5 mL Serum Separator (tall gold-top) tube


Minimum Volume
0.3 mL


Other Acceptable Specimens
Serum separator (small gold-top)


Transport Temperature
Refrigerated


Specimen Stability
Refrigerated: 7 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis


Methodology
Chemiluminescence Immunoassay

Setup Schedule
Monday - Friday


Report Available
2 Business Days


Reference Range
Negative (Non-reactive)


Clinical Significance
This assay is used to detect the total antibody to the core component of the Hepatitis B virus (anti-HBc). This assay detects the total core antibody (both IgG and IgM), but cannot distinguish between the two. It can be used as an aid in the diagnosis of individuals with either acute or chronic hepatitis B virus and is typically used in conjunction with other HBV serological markers. The HBc antibody may even outlast Hepatitis B surface antibody and occasionally may be the only marker of past infection to Hepatitis B.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.