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Lipid Panel, Reflex to Direct LDL
MessagePerforming Lab: Central Lab, Hudson, Lakeview, Regions, Sartell, Westfields
Test Code
3707
Alias/See Also
Sunquest: LIPDR
CPT Codes
80061
Includes
Hours Fasting; Total Cholesterol; Triglyceride; HDL; LDL; Non-HDL Cholesterol If Triglyceride result is between 400-1300 mg/dL, a Direct LDL (LDLDR) will automatically be ordered. Direct LDL is performed at Central Lab and Regions.
Preferred Specimen
400 uL Lithium Heparin Plasma (light green-top) tube
Minimum Volume
23 uL (does not include dead volume)
Other Acceptable Specimens
Serum (gold-top, red-top, red/gray-top), Lithium Heparin (light green-top) on ICE
Instructions
Ordering:
Hours Fasting must be provided when ordering. Fasting is defined as “Nothing consumed in the past 12 hours except water”.
Hours Fasting must be provided when ordering. Fasting is defined as “Nothing consumed in the past 12 hours except water”.
Transport Temperature
Refrigerated
Specimen Stability
Room Temperature: < 2 days
Refrigerated: < 7 days
Frozen: < 3 months at -20 C
Lakeview: Refrigerated (2 days)
Refrigerated: < 7 days
Frozen: < 3 months at -20 C
Lakeview: Refrigerated (2 days)
Methodology
Enzymatic (Cholesterol)
Glycerol Phosphate Oxidase (Triglyceride)
Accelerator Selective Detergent (HDL)
Colorimetric (Cholesterol, Triglyceride, HDL), LDL Calculation (Cholesterol - (Triglyceride/5) - HDL)
Setup Schedule
Hospital: Daily
Clinics: Monday - Friday
Clinics: Monday - Friday
Report Available
Same day.
Reference Range
Cholesterol:
0 - 199 mg/dL
Triglyceride:
0 - 149 mg/dL
HDL:
Normal: > 40 mg/dL
LDL:
Normal: < 130 mg/dL
Borderline High: 130 - 159 mg/dL
High: 160 - 189 mg/dL
Very High: = 190 mg/dL
For patients at very high risk or with known cardiovascular disease, an LDL goal of 70 mg/dl is a therapeutic option.
0 - 199 mg/dL
Triglyceride:
0 - 149 mg/dL
HDL:
Normal: > 40 mg/dL
LDL:
Normal: < 130 mg/dL
Borderline High: 130 - 159 mg/dL
High: 160 - 189 mg/dL
Very High: = 190 mg/dL
For patients at very high risk or with known cardiovascular disease, an LDL goal of 70 mg/dl is a therapeutic option.
Clinical Significance
Total LDL and HDL cholesterol, in conjunction with a triglyceride determination, provide valuable information for the risk of coronary artery disease. Total serum cholesterol analysis is useful in the diagnosis of hyperlipoproteinemia, atherosclerosis, hepatic and thyroid diseases. HDL cholesterol levels are inversely related to the risk for cardiovascular disease.
