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Cholesterol, Total
MessagePerforming Lab: Central Lab, Hudson, Lakeview, Regions, Sartell, Westfields
Test Code
0111
Alias/See Also
Sunquest: CHOL
CPT Codes
82465
Preferred Specimen
0.2 mL Lithium Heparin Plasma (light green-top) tube
Minimum Volume
0.1 mL
Other Acceptable Specimens
Serum (gold-top, red-top, red/gray-top), Lithium Heparin (light green-top) on ICE
Instructions
Collection:
Does NOT require a 12-hour fast
Does NOT require a 12-hour fast
Transport Temperature
Refrgerated
Specimen Stability
Room Temperature: Not Recommended
Refrigerated: 3 days
Frozen: 3 weeks
Refrigerated: 3 days
Frozen: 3 weeks
Methodology
Colorimetric
Setup Schedule
Hospital: Daily
Clinics: Monday - Friday
Clinics: Monday - Friday
Report Available
Same day.
Reference Range
0 - 199 mg/dL
Clinical Significance
Cholesterol is present in tissues and in serum and plasma either as cholesterol or as cholesterol esters bound to proteins. Cholesterol is an essential structural component of cell membranes and the outer layer of plasma lipoproteins and is the precursor of all steroid hormones, including sex and adrenal hormones, bile acids, and vitamin D.
Cholesterol measurements are used to evaluate the risk of developing coronary artery occlusion, atherosclerosis, myocardial infarction, and cerebrovascular disease. Coronary atherosclerosis correlates with a high cholesterol level. Cholesterol concentrations are increased in primary hypercholesterolemia; secondary hyperlipoproteinemia, including nephrotic syndrome; primary biliary cirrhosis; hypothyroidism; and in some cases diabetes mellitus. Low cholesterol concentrations may be found in malnutrition, malabsorption, advanced malignancy, and hyperthyroidism. Serum cholesterol concentration depends on many factors, including age, gender, and diet.
Cholesterol measurements are used to evaluate the risk of developing coronary artery occlusion, atherosclerosis, myocardial infarction, and cerebrovascular disease. Coronary atherosclerosis correlates with a high cholesterol level. Cholesterol concentrations are increased in primary hypercholesterolemia; secondary hyperlipoproteinemia, including nephrotic syndrome; primary biliary cirrhosis; hypothyroidism; and in some cases diabetes mellitus. Low cholesterol concentrations may be found in malnutrition, malabsorption, advanced malignancy, and hyperthyroidism. Serum cholesterol concentration depends on many factors, including age, gender, and diet.