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Chloride
MessagePerforming Lab: Central Lab, Hudson, Lakeview, Regions, Sartell, Westfields
Test Code
0110
Alias/See Also
Sunquest;CL
CPT Codes
82435
Preferred Specimen
0.1 mL Lithium Heparin Plasma (light green-top) tube
Minimum Volume
65 uL
Other Acceptable Specimens
Serum (gold-top, red-top, red/gray-top), Lithium Heparin (light green-top) on ICE
Transport Temperature
Refrgerated
Specimen Stability
Room Temperature (7 days), Refrigerated (7 days), Frozen (1 year)
Methodology
ion-specific electrode diluted (direct)
Setup Schedule
Hospital: Daily
Clinics: Monday - Friday
Clinics: Monday - Friday
Report Available
Same day.
Reference Range
98 - 109 mmol/L
Clinical Significance
Chloride is the major anion in the extracellular water space; its physiological significance is in maintaining proper body water distribution, osmotic pressure, and normal anion-cation balance in the extracellular fluid compartment.
Chloride is increased in dehydration, in renal tubular acidosis (hyperchloremia metabolic acidosis), and in excessive infusion of isotonic saline. Chloride is decreased in overhydration, chronic respiratory acidosis, salt-losing nephritis, metabolic alkalosis, and congestive heart failure.
Chloride is increased in dehydration, in renal tubular acidosis (hyperchloremia metabolic acidosis), and in excessive infusion of isotonic saline. Chloride is decreased in overhydration, chronic respiratory acidosis, salt-losing nephritis, metabolic alkalosis, and congestive heart failure.