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Alanine Aminotransferase (ALT)
MessagePerforming Lab: Central Lab, Hudson, Lakeview, Regions, Sartell, Westfields
Test Code
0129
Alias/See Also
Sunquest: ALT; SGPT
CPT Codes
84460
Preferred Specimen
0.1 mL Lithium Heparin Plasma (light green-top) tube
Minimum Volume
56 uL
Other Acceptable Specimens
Serum (gold-top) tube
Instructions
Processing:
Centrifuge specimens within 2 hours of collection
Centrifuge specimens within 2 hours of collection
Transport Temperature
Refrigerated
Specimen Stability
Room Temperature (3 days), Refrigerated (7 days), Frozen (2 months)
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolyzed samples
Methodology
NADH - without P-5'-P
Setup Schedule
Hospital: Daily
Clinics: Monday - Friday
Clinics: Monday - Friday
Report Available
Same day
Reference Range
| Reference Range | Critical Value | |
| 0 - 55 U/L | >999 U/L |
Clinical Significance
Alanine aminotransferase is present in high activity in liver, skeletal muscle, heart, and kidney. Serum ALT increases rapidly in liver cell necrosis, hepatitis, hepatic cirrhosis, liver tumors, obstructive jaundice, Reye’s syndrome, extensive trauma to skeletal muscle, myositis, myocarditis, and myocardial infarction.
