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Iron Profile
MessagePerforming Lab: Central Lab, Lakeview, Regions, Sartell
Test Code
0121
Alias/See Also
Sunquest: IRON
CPT Codes
83540, 83550
Includes
Iron;Total Iron Binding Capacity (calculated);%Saturation (calculated); Transferrin (measured)
Preferred Specimen
0.5 mL Lithium Heparin (light green-top) tub
Minimum Volume
0.2 mL
Other Acceptable Specimens
Gold, Red, Red/Gray-top
Transport Temperature
Refrigerated
Specimen Stability
Refrigerated: 3 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis, Plasma specimens
Methodology
Two-point Rate (Iron)
Immunotubidometric(Transferrin)
% Sat Calculation [(Iron/TIBC) x 100]
Setup Schedule
Hospital: Daily
Clinics: Monday - Friday
Clinics: Monday - Friday
Report Available
Same day
Reference Range
Site | Sex | Test | Reference Range | Critical |
Regions, Central Lab, St Cloud,Lakeview | F | Iron | 50-170 | >350 |
Regions, Central Lab, St Cloud, Lakeview | M | Iron | 65-175 | >350 |
Regions, Central Lab, St Cloud, Lakeview | M/F | TIBC | 240-430 | na |
Regions, Central Lab, St Cloud, Lakeview | M/F | SAT | 10-50 | na |
Regions, Central Lab, St Cloud, Lakeview | F | TRANF | 180-382 | na |
Regions, Central Lab, St Cloud, Lakeview | M | TRANF | 174-364 | na |
Clinical Significance
The measurements of serum iron and serum iron-binding capacity are useful in the differential diagnosis of anemia, iron deficiency anemia, thalassemia, possible sideroblastic anemia, and iron poisoning. Total iron-binding capacity (TIBC) in serum, representing the iron-binding capacity of transferrin, is a useful index of nutritional status. Serum TIBC varies in disorders of iron metabolism. Serum TIBC is increased in iron deficiency and decreased in chronic inflammatory disorders, malignancies and hemochromatosis. Indications for transferrin quantitation include: screening for nutritional status; differential diagnosis of anemia; and monitoring anemia treatment. Iron deficiency and iron overload are best diagnosed using a combination of iron, transferrin, and ferritin determinations.