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Lipase
MessagePerforming Lab: Central Lab, Hudson, Lakeview, Regions, Sartell, Westfields
Test Code
0535
Alias/See Also
Sunquest: LIPAS
CPT Codes
83690
Preferred Specimen
100 uL Lithium Heparin Plasma (light green-top) tube
Minimum Volume
5 uL (does not include dead volume)
Other Acceptable Specimens
Serum separator (gold-top), Lithium Heparin (light green-top) on ICE, Red, Red/Gray
Transport Temperature
Refrigerated
Specimen Stability
Room Temperature: < 7 days
Refrigerated: < 7 days
Frozen: < 1 year at -20 C
Refrigerated: < 7 days
Frozen: < 1 year at -20 C
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross Lipemia, Hemolysis
Methodology
Quinone Dye
Setup Schedule
Hospital: Daily
Clinics: Monday - Friday
Clinics: Monday - Friday
Report Available
Same day.
Reference Range
8-78 U/L | |
Clinical Significance
Lipase is a digestive enzyme that is mainly produced by the acinar cells of the exocrine pancreas. Its physiological role is to hydrolyze the long-chain triglycerides in the small intestine. Serum lipase increases rapidly in patients with acute and recurrent pancreatitis, pancreatic abscess or pseudocyst, pancreatic trauma, pancreatic cancer, common-bile-duct obstruction, and ingestion of drugs that are toxic to the pancreas. It is also increased by most inflammatory conditions in the abdominal cavity, biliary tract disease, abdominal abscesses, and renal failure. Lipase is more specific than total amylase in the diagnosis of acute pancreatitis.