| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Creatine Kinase, Total (CK)
MessagePerforming Lab: Central Lab, St Cloud, Hudson, Lakeview, Regions, Westfields
Test Code
0113
Alias/See Also
Sunquest: CK; Creatine Phosphokinase, CPK
CPT Codes
82550
Preferred Specimen
0.1 mL Lithium Heparin Plasma (light green-top) tube
Minimum Volume
54 uL
Other Acceptable Specimens
Serum (gold-top, red-top, red/gray-top), Lithium Heparin (light green-top) on ICE
Transport Temperature
Refrgerated
Specimen Stability
Room Temperature (2 days), Refrigerated (7 days), Frozen (not recommended)
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross Hemolysis
Methodology
NAC N-acetyl-L-cystain
Setup Schedule
Hospital: Daily
Clinics: Monday - Friday
Clinics: Monday - Friday
Report Available
Same day.
Reference Range
| Male | Female | |
| 30 - 200 U/L | 29 - 168 U/L |
Clinical Significance
Creatine kinase is a cellular enzyme with a wide tissue distribution. CK is found mainly in skeletal and cardiac muscle. CK’s physiological role is associated with ATP generation for contractile or transport systems.
Serum CK is almost always increased following acute myocardial infarction or skeletal muscle damage. The enzyme is commonly elevated in myocarditis of any cause, cerebrovascular accidents, rhabdomyolysis, polymyositis, and acute physical exertion. CK is also increased in the muscular dystrophies; in Duchenne’s muscular dystrophy, CK elevations of 20–200 times normal are common. Low CK may reflect decreased muscle mass or muscle wasting. Low serum CK activities are common in the elderly, in the bedridden, and in patients with advanced malignancy.
Serum CK is almost always increased following acute myocardial infarction or skeletal muscle damage. The enzyme is commonly elevated in myocarditis of any cause, cerebrovascular accidents, rhabdomyolysis, polymyositis, and acute physical exertion. CK is also increased in the muscular dystrophies; in Duchenne’s muscular dystrophy, CK elevations of 20–200 times normal are common. Low CK may reflect decreased muscle mass or muscle wasting. Low serum CK activities are common in the elderly, in the bedridden, and in patients with advanced malignancy.
