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Prealbumin
MessagePerforming Lab: Regions
Test Code
3106
Alias/See Also
Sunquest: PALB
CPT Codes
84134
Preferred Specimen
0.2 mL Serum separator (gold-top, red-top, red/gray-top) tube
Minimum Volume
0.1 mL
Transport Temperature
Refrigerated
Specimen Stability
Room Temperature: 1 day
Refrigerated: 2 weeks
Frozen: Not Recommended
Refrigerated: 2 weeks
Frozen: Not Recommended
Methodology
Blanked Endpoint
Setup Schedule
Daily
Report Available
Same day.
Reference Range
17.6 - 36.0 mg/dL
Clinical Significance
Prealbumin (thyroxin-binding prealbumin, transthyretin) transports the thyroid hormones thyroxin (T4) and triiodothyronine (T3). It also transports vitamin A in association with retinol binding globulin. Prealbumin is a negative acute-phase reactant with decreased levels found in inflammation, malignancy, cirrhosis of the liver, and protein-wasting diseases of the gut or kidneys. Increased concentrations can be seen in Hodgkin’s disease or a prealbumin-producing tumor. Prealbumin is a sensitive indicator of nutritional status due to its short half-life, high tryptophan content, high proportion of essential-to-nonessential amino acids, and small pool size.