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Lactate
MessagePerforming Lab: Hudson, Lakeview, Regions, Westfields
Test Code
0530
Alias/See Also
Sunquest; LACT; Lactic Acid, L-Lactate
CPT Codes
83605
Preferred Specimen
0.2 mL Lithium Heparin (light green-top) on ICE
Minimum Volume
0.1 mL
Other Acceptable Specimens
Flouride Oxalate Plasma (gray-top)
Instructions
Collection:
Collect and keep specimen on ice until processing.
Collect without the use of a tourniquet or within 3 minutes of applying the tourniquet, but before releasing the tourniquet. Do not allow patient to clench/unclench hand; this builds up lactic acid. Deliver to laboratory immediately. Room temperature samples must be received and assayed within 15 minutes of collection.
Collect and keep specimen on ice until processing.
Collect without the use of a tourniquet or within 3 minutes of applying the tourniquet, but before releasing the tourniquet. Do not allow patient to clench/unclench hand; this builds up lactic acid. Deliver to laboratory immediately. Room temperature samples must be received and assayed within 15 minutes of collection.
Transport Temperature
Ice Slush or Refrigerated if Lithium Heparin
If you use Gray tube it must be sent on ice.
If you use Gray tube it must be sent on ice.
Specimen Stability
Refrigerated: 2 weeks
Frozen: 1 month
Frozen: 1 month
Methodology
Colorimetric or Bichromatic Endpoint (Lakeview)
Setup Schedule
Daily
Report Available
Same day.
Reference Range
Reference Range | Critical Value | |
0.5-2.2 mmol/L | >4.0 mmol/L | |
Clinical Significance
The concentration of lactate in the blood is dependent on the rate of production in muscle cells and erythrocytes and the rate of metabolism in the liver. Lactic acidosis usually results from overproduction or underutilization of lactate. Elevated lactate levels can occur as a result of tissue hypoxia; diabetes mellitus; phenformin therapy; malignancies; glycogen storage disease; ethanol, methanol, or salicylate ingestion; and metabolic acidosis