Fibrinogen Activity

Message
Performing Lab: Hudson, Lakeview, Regions, Westfields


Test Code
3520


Alias/See Also
Sunquest: FIBA


CPT Codes
85384

Preferred Specimen
2.7 mL (in 3 mL tube) 3.2% Sodium Citrate Plasma (light blue-top) tube filled to fill line on the tube


Minimum Volume
1.0 mL


Other Acceptable Specimens
1.0 mL platelet poor plasma (Frozen)


Instructions
Collection:  Samples with a hematocrit > 55% require a special anticoagulant adjusted tube for high hematocrits.
Processing:  Freeze an aliquot of plasma at -20°C if not performed within 4 hours of collection


Transport Temperature
Room Temperature or Frozen if > 4 hours old


Specimen Stability
Room Temperature: 4 hours    
Refrigerated: 4 hours    
Frozen (-20C): 72 hours
Frozen (-80C): 2 Weeks


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolyzed or Clotted Samples, Samples do not meet the minimum draw requirements, Samples exceed maximum draw requirements, Samples with hematocrit >55% not collected with the special tube.


Methodology
Clot Based

Setup Schedule
Daily


Report Available
Same day.


Reference Range
175-420 mg/dL   
Critical Value: <=100 mg/dL


Clinical Significance
An increase of the fibrinogen level is observed in cases of pregnancy, diabetes, inflammatory syndromes and obesity. A decrease of the fibrinogen level is observed in DIC, fibrinolysis. Furthermore, fibrinogen seems to be involved in the pathogenicity of thrombotic cardiovascular events.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.