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Electrophoresis, Random Urine Cascade
MessagePerforming Lab: Central Lab
Test Code
3636
Alias/See Also
Sunquest: CRUPE; Random Urine Protein Electrophoresis Cascade
CPT Codes
84166, 84156
Includes
If more than Albumin is seen on the electrophoresis, a Urine Immunofixation (IFERU) will automatically be ordered, performed and billed by the laboratory.
24 Hour or First Morning collections have a higher probability of detecting abnormalities.
24 Hour or First Morning collections have a higher probability of detecting abnormalities.
Preferred Specimen
20.0 mL Random Urine
Minimum Volume
10.0 mL Random Urine
Instructions
Processing: Do not add preservatives to the specimen
Transport Temperature
Refrigerated
Specimen Stability
Refrigerated: 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Inadequate sample volume
Preservative present in sample
Preservative present in sample
Methodology
Agarose Gel Electrophoresis
Setup Schedule
Tuesday and Thursday
Report Available
Within 5 days
Limitations
24 Hour or First Morning collections have a higher probability of detecting abnormalities
Reference Range
No Monoclonal Protein Present
No expected values are defined for the urine protein fractions
No expected values are defined for the urine protein fractions
Clinical Significance
Electrophoresis is used to identify the presence of abnormal proteins, to identify the absence of normal proteins, and to determine when different groups of proteins are increased or decreased. Urine protein electrophoresis may be ordered to help diagnose the cause and estimate the severity of protein excretion due to kidney damage or disease. This damage or disease may be due to diabetes, chronic inflammation, an autoimmune condition, or a malignancy. Electrophoresis is not usually necessary to assess the loss of small to moderate amounts of protein due to temporary conditions, such as a urinary tract infection or an acute inflammation.
