IgA (Immunoglobulin A)

Message

Performing Lab: Central Lab, Regions

Test Code

0515

Alias/See Also

Sunquest: IGA

CPT Codes
82784

Preferred Specimen

0.6 mL Lithium Heparin Plasma (light green-top) tube

Minimum Volume

0.3 mL

Other Acceptable Specimens

Serum separator (gold-top), Red, Red/Gray

Transport Temperature

Refrigerated

Specimen Stability

Refrigerated: 7 days

Methodology
Immunoturbidimetric

Setup Schedule

Monday - Friday

Report Available

Same day

Limitations

Abnormally elevated levels of monoclonal immunoglobulin, as in cases of multiple myeloma, amyloidosis, or other lymphoproliferative diseases may interfere with the quantification of IgA

Reference Range

Age	Sex	Reference Range
0-4 Months	Female	1-34
4 Months-2 Years	Female	8-91
2 Years-13 Years	Female	21-282
13 Years-61 Years	Female	65-421
Greater than 61 Years	Female	69-517
0-4 Months	Male	1-34
4 Months- 2 Years	Male	8-91
2 Years - 13 Years	Male	21-291
13 Years - 61 Years	Male	63-484
Greater than 61 Years	Male	101-645

Clinical Significance

IgA represents 10 to 15% of serum immunoglobulin. Despite the uncertainty of its exact role in serum, its part in resistance against infection is due to the prevention of adherence of bacteria, or to the inhibition of attachment and penetration of viruses. IgA may be elevated in recurrent infections and anaphylactic transfusion reactions. Increases are also associated with chronic liver disease, chronic infections, neoplasia of the lower GI tract and inflammatory bowel disease. IgA may be used as an aid in the diagnosis of ataxia telangiectasia, in the differentiation of M-components in multiple myeloma, and in the evaluation of progression of IgA myeloma. Decreased levels of IgA may be found in isolated genetic deficiency, combined immunodeficiency disorders, non-IgA multiple myeloma or macroglobulinemia.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.