| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Bilirubin, Total
MessagePerforming Lab: Central Lab, Hudson, Lakeview, Regions, Sartell, Westfields
Test Code
0106
Alias/See Also
Sunquest: BILT; Total Bilirubin
CPT Codes
82247
Preferred Specimen
100 uL Lithium Heparin Plasma (light green-top) tube
Minimum Volume
- 55 uL
Other Acceptable Specimens
Serum (gold-top, red-top, red/gray-top), Lithium Heparin (light green-top) on ICE
Instructions
Protect from light. Exposure to light may falsely decrease result.
Transport Temperature
Refrigerated
Specimen Stability
Room Temperature (24 hours), Refrigerated (7 days), Frozen (6 months at -20o C)
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross Hemolysis
Methodology
Diazonium Saturation
Setup Schedule
Hospital: Daily
Clinics: Monday - Friday
Clinics: Monday - Friday
Report Available
Same day.
Limitations
Bilirubin is photosensitive and samples should be protected from both sunlight and fluorescent light to avoid photo-degradation.
Reference Range
| Ref Range | Critical Value | |
| >21 Days: 0.2 - 1.2 mg/dL | <31 Days: >14.9 mg/dL |
Clinical Significance
Total bilirubin in serum and plasma is the sum of unconjugated bilirubin (Bu), mono- and diglucuronide conjugated bilirubin (Bc), and delta bilirubin (DELB), a bilirubin fraction covalently bound to albumin. With the exception of anicteric jaundice, total serum bilirubin is invariably increased in jaundice. Causes of jaundice are pre-hepatic, resulting from various hemolytic diseases; hepatic, resulting from hepatocellular injury or obstruction; and post-hepatic, resulting from obstruction of the hepatic or common bile ducts. Jaundice has been classified as unconjugated (indirect) and conjugated (direct) hyperbilirubinemia. Increased plasma conjugated bilirubin occurs with hepatobiliary disorders, including intrahepatic and extrahepatic biliary tree obstruction, liver cell damage, Dubin-Johnson syndrome, and Rotor syndrome.
