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Iron
MessagePerforming Lab: Central Lab, Lakeview, Regions
Test Code
3775
Alias/See Also
Sunquest: FE
CPT Codes
83540
Preferred Specimen
0.1 mL Lithium Heparin Plasma (light green-top) tube
Minimum Volume
70 uL
Other Acceptable Specimens
Serum separator (gold-top), Lithium Heparin (light green-top) on ICE (ALL SITES)
Red, Red/Gray (Lakeview only)
Red, Red/Gray (Lakeview only)
Transport Temperature
Refrigerated
Specimen Stability
Room Temperature (7 days), Refrigerated (3 weeks), Frozen (1 year)
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis
Methodology
Two-point Rate
Setup Schedule
Hospital: Daily
Clinics: Monday - Friday
Clinics: Monday - Friday
Report Available
Same day.
Limitations
Do not use hemolyzed specimens because of the high concentration of iron in hemoglobin.
Reference Range
Gender | Ref. Range | Critical Value | |
>= 350 mcg/dL | |||
Female | 50 - 170 mcg/dL | ||
Male | 65 - 175 mcg/dL |
Clinical Significance
Most body iron is found in hemoglobin. The serum measurement of iron is useful in the differential diagnosis of anemia, iron deficiency anemia, thalassemia, possible sideroblastic anemia, and iron poisoning.
Serum iron is increased in hemosiderosis, hemolytic anemias, thalassemia, sideroblastic anemias, hepatitis, acute hepatic necrosis, hemochromatosis, inappropriate iron therapy, and iron poisoning.
Serum iron is decreased in cases of insufficient dietary iron, chronic blood loss, inadequate absorption of iron, impaired release of iron stores (commonly observed in inflammation), infection, and chronic diseases.
Serum iron is increased in hemosiderosis, hemolytic anemias, thalassemia, sideroblastic anemias, hepatitis, acute hepatic necrosis, hemochromatosis, inappropriate iron therapy, and iron poisoning.
Serum iron is decreased in cases of insufficient dietary iron, chronic blood loss, inadequate absorption of iron, impaired release of iron stores (commonly observed in inflammation), infection, and chronic diseases.