Testosterone, Total

Message

Performing Lab: Central Lab

Test Code

0199

Alias/See Also

Sunquest: TESTO

CPT Codes
84403

Preferred Specimen

0.3 mL Serum Separator (gold-top) tube

Minimum Volume

0.2 mL

Transport Temperature

Refrigerated

Specimen Stability

Refrigerated: 5 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Plasma is not an acceptable specimen type. Hemolysis, Lipemia

Methodology
Chemiluminescence

Setup Schedule

Monday - Friday

Report Available

Same Day

Limitations

FemaleFemale reference ranges based on a non-pregnant population. SHBG production is stimulated by estradiol and pregnant women have markedly higher SHBG concentrations due to their increased estrogen production.

Reference Range

20 - 69 years (male): 200 - 745 ng/dL
20 - 46 years (female): 17 - 88 ng/dL
47 - 91 years (female): 10 - 66 ng/dL

Clinical Significance

Testosterone is produced by the adrenals, the theca cells in the ovary and the leydig cells in the testes. As much as 97% of circulating testosterone is bound to serum proteins such as sex hormone binding globulin (SHBG). In the male, testosterone stimulates the maturation of genitalia and secondary sexual characteristics and its measurement is used to investigate sexual dysfunction in juveniles and adults. In females testosterone concentrations are much lower and an elevated concentration may indicate polycystic ovarian syndrome among other conditions. Clinical symptoms of testosterone excess in females include infertility, amenorrhea, obesity and hirsutism.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.