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Sex Hormone Binding Globulin
MessagePerforming Lab: Central Lab
Test Code
4784
Alias/See Also
Sunquest: SBG
CPT Codes
84270
Preferred Specimen
0.3 mL Serum Separator (gold-top) tube
Minimum Volume
0.2 mL
Other Acceptable Specimens
Red, Red/Gray
Transport Temperature
Refrigerated
Specimen Stability
Refrigerated: 5 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Plasma is not an acceptable specimen type. Hemolyzed or lipemic samples.
Methodology
Chemiluminescence
Setup Schedule
Monday - Friday
Report Available
Same Day
Limitations
For patients presenting with cirrhosis or sub-clinical thyroid conditions, carefully evaluate the results as these conditions can potentially cause erroneous SHBG results
Reference Range
20 - 69 years (male): 16 - 70 nmol/L
20 - 46 years (female): 18 - 136 nmol/L
47 - 91 years (female): 17 - 125 nmol/L
20 - 46 years (female): 18 - 136 nmol/L
47 - 91 years (female): 17 - 125 nmol/L
Clinical Significance
Sex hormone binding globulin (SHBG) is a glycoprotein responsible for blood transport of testosterone and estradiol. The measurement of SHBG can be an important indicator of chronic or excessive androgenic activity where clinical symptoms would seem to indicate androgen excess, but androgen levels are normal.
